| Biomarker ID | 941 |
| PMID | 22759231 |
| Year | 2012 |
| Biomarker | Mutation Status of KLK3 (-5429 T/G (rs2569733)) |
| Biomarker Basis | Mutation Based |
| Biomolecule | Mutation |
| Source | Blood |
| Subjects | Humans |
| Regulation | NA |
| Odds Ratio/Hazard Ratio/Relative Risk | OR: Univariate Analysis: [1.93 (95% CI: 1.18–3.16)]; Multivariate Analysis: [0.29 (95% CI: 0.11–0.77)] |
| Effect on Pathways | NA |
| Experiment | Biochemical Recurrence Vs no Biochemical Recurrence (5 years) |
| Type of Biomarker | Prognostic |
| Cohort | 670 patients were selected for the study out of which 581 had no Biochemical Recurrence and 89 had |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | Univariate Analysis: <0.01 ; Multivariate Analysis : p=0.013 |
| Method Used | multiplex-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | KLK3 |