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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID938
PMID22674214
Year2012
BiomarkerPCA3 + TMPRSS2:ERG gene fusion
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
ExperimentNormal adjacent to Prostate (NP) Vs Low Grade PCa
Type of BiomarkerDiagnostic
Cohort48 Benign Prostatic Hyperplasia (BPH), 32 Normal adjacent to Prostate (NP), and 48 PCa samples (20 Low grade, 28 High Grade) were taken in the study.
Senstivity9362%
Specificity9750%
AUCNA
AccuracyNA
Level Of SignificanceNA
Method Usedquantitative real time polymerase chain reactions (qRT-PCR)
ClinicalNo
RemarksLG: GS>7, HG: 7 and above
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NamePCA3, ERG