Biomarker ID | 936 |
PMID | 22674214 |
Year | 2012 |
Biomarker | PCA3 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated (RQ = NP: 7.4 Vs LG = 202) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Normal adjacent to Prostate (NP) Vs Low Grade PCa |
Type of Biomarker | Diagnostic |
Cohort | 48 Benign Prostatic Hyperplasia (BPH), 32 Normal adjacent to Prostate (NP), and 48 PCa samples (20 Low grade, 28 High Grade) were taken in the study. |
Senstivity | 8542% |
Specificity | 9875% |
AUC | 0.895 (95% CI: 0.82–0.97) |
Accuracy | NA |
Level Of Significance | <0.005 |
Method Used | quantitative real time polymerase chain reactions (qRT-PCR) |
Clinical | No |
Remarks | LG: GS>7, HG: 7 and above |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | PCA3 |