Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 933 |
| PMID | 22619380 |
| Year | 2012 |
| Biomarker | Modification Status of RNF220 |
| Biomarker Basis | Mutation Based |
| Biomolecule | cirDNA |
| Source | Plasma |
| Subjects | Humans |
| Regulation | Highly modified in PCa Patients (Control: 55% |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | PCA Vs BPH |
| Type of Biomarker | Diagnostic |
| Cohort | Training Set: prostate cancer patients with locally confined disease (n = 19), in patients with benign prostate hyperplasias (n = 20) and in men without any known prostate disease (n = 20).; Validation Set: 20 prostate cancer patients and 18 BPH patients (Results shown for validation set) |
| Senstivity | 61% |
| Specificity | 71% |
| AUC | 0.562 |
| Accuracy | NA |
| Level Of Significance | p = 1 *10^-4 |
| Method Used | Real-time PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on Independent Patient Cohort |
| Technical Name | RNF220 |