Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
Detailed Information | |
---|---|
Biomarker ID | 933 |
PMID | 22619380 |
Year | 2012 |
Biomarker | Modification Status of RNF220 |
Biomarker Basis | Mutation Based |
Biomolecule | cirDNA |
Source | Plasma |
Subjects | Humans |
Regulation | Highly modified in PCa Patients (Control: 55% |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | PCA Vs BPH |
Type of Biomarker | Diagnostic |
Cohort | Training Set: prostate cancer patients with locally confined disease (n = 19), in patients with benign prostate hyperplasias (n = 20) and in men without any known prostate disease (n = 20).; Validation Set: 20 prostate cancer patients and 18 BPH patients (Results shown for validation set) |
Senstivity | 61% |
Specificity | 71% |
AUC | 0.562 |
Accuracy | NA |
Level Of Significance | p = 1 *10^-4 |
Method Used | Real-time PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on Independent Patient Cohort |
Technical Name | RNF220 |