| Biomarker ID | 932 |
| PMID | 22619380 |
| Year | 2012 |
| Biomarker | Modification Status of RNF219 |
| Biomarker Basis | Mutation Based |
| Biomolecule | cirDNA |
| Source | Plasma |
| Subjects | Humans |
| Regulation | Highly modified in PCa Patients (Control: 55% |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | PCA VS no history of prostate disease |
| Type of Biomarker | Diagnostic |
| Cohort | Training Set: prostate cancer patients with locally confined disease (n = 19), in patients with benign prostate hyperplasias (n = 20) and in men without any known prostate disease (n = 20). |
| Senstivity | 89% |
| Specificity | 61% |
| AUC | 0.794 |
| Accuracy | NA |
| Level Of Significance | p=3 *10^-41 |
| Method Used | Real-time PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on Independent Patient Cohort |
| Technical Name | OBI1 |