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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID930
PMID22615945
Year2012
BiomarkerTriosephosphate isomerase 1 (TPI1); Spondin-2 (SPON-2); Thrombospondin 1, N-Terminal Domain (THBS1); Phosphoglycerate mutase 1 (PGAM1); Syndecan binding protein 1 (ST1); Peroxiredoxin 1 (PRDX1); Nucleophosmin- isoform CRA_c (NPM1)
Biomarker BasisExpression Based
BiomoleculeProtein
SourceSerum
SubjectsCell Lines
RegulationDifferentially Expressed in PCA
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
ExperimentBPH-1, LNCaP Vs C4-2
Type of BiomarkerDiagnostic
Cohort3 Prostate cancer Cell lines: BPH-1, LNCaP and C4-2 were taken into consideration for this study.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.05
Method Usedtwo-dimensional gel electrophoresis (2-DE) coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS)
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on Independent Patient Cohort
Technical NameTPI1, SPON2, THBS1, PGAM1, NPM1