Biomarker ID | 906 |
PMID | 22505341 |
Year | 2012 |
Biomarker | Fusion status of TMPRSS2-ERG and TERT expression |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | TMPRSS2–ERG and TERT-negative tumors had significantly lower rate of recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | HR: 7.33 (95% CI: 0.98-54.99) |
Effect on Pathways | NA |
Experiment | Biochemical Recurrence Free Survival |
Type of Biomarker | Prognostic |
Cohort | 20 PCa patients with recurrence and 118 without recurrence were included in this study |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.025 |
Method Used | RT-PCR |
Clinical | No |
Remarks | Biochemical recurrence was defined as a PSA level of ≥0.2 ng/mL |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | TMPRSS2, ERG, TERT |