Biomarker ID | 905 |
PMID | 22505341 |
Year | 2012 |
Biomarker | ERG |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in TERT positive cases |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | TERT positive compared to TERT negative in Prostate cancer |
Type of Biomarker | Prognostic |
Cohort | Prostate specimens and urine sediments from 179 previously untreated patients with pT2-pT3 stage PCa were analyzed. 75 were TERT positive cases and 83 were TERT negative cases |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.016 |
Method Used | RT-PCR |
Clinical | No |
Remarks | ERG and SPINK1 expression levels were not different in tumor versus nontumor prostate tissues |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | ERG |