Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 888 |
| PMID | 22397815 |
| Year | 2012 |
| Biomarker | NK3 homeobox 1 (NKX3-1) |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in Gleason Grade 3 |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Normal Prostate Vs Gleason Grade 3 |
| Type of Biomarker | Diagnostic |
| Cohort | 47 Norwegian patients were selected and randomly given placebo or genistein. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.012 |
| Method Used | Immunohistochemistry |
| Clinical | Yes |
| Remarks | NA |
| Clinical Trial Number | NCT00546039 |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NKX3-1 |