Biomarker ID | 887 |
PMID | 22397815 |
Year | 2012 |
Biomarker | kallikrein-related peptide 4 (KLK4) |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Downregulated in genistein treated patients compared to placebo treated |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Treated with Placebo Vs Treated with Genistein (30mg capsule) |
Type of Biomarker | Predictive |
Cohort | 47 Norwegian patients were selected and randomly given placebo or genistein. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.033 |
Method Used | real-time semiquantitative PCR |
Clinical | Yes |
Remarks | NA |
Clinical Trial Number | NCT00546039 |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | KLK4 |