| Biomarker ID | 857 |
| PMID | 22298030 |
| Year | 2012 |
| Biomarker | miR-1285 |
| Biomarker Basis | Expression Based |
| Biomolecule | miRNA |
| Source | Plasma |
| Subjects | Humans |
| Regulation | Upregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:- Golgi apparatus; regulation of Ras protein signal transduction; regulation of small GTPase mediated signal transduction; synapse |
| Experiment | prostate cancer Vs benign prostatic hyperplasia |
| Type of Biomarker | Diagnostic |
| Cohort | Training set: 25 patients with prostate cancer, 17 with Benign prostatic hyperplasia. Validation Set: 80 CaP, 44 BPH, and 54 healthy controls |
| Senstivity | 61.25% |
| Specificity | 57.41% |
| AUC | 0.644 (95% CI: 0.550–0.739; |
| Accuracy | NA |
| Level Of Significance | Training: p<0.0001 |
| Method Used | Training Set: Microarrays, Validation set; qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on Independent Patient Cohort |
| Technical Name | miR-1285 |