Biomarker ID | 856 |
PMID | 22298030 |
Year | 2012 |
Biomarker | miR-940 |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Plasma |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-mintracellular transport;Golgi apparatus; cell junction; synapse; Golgi membrane |
Experiment | prostate cancer Vs benign prostatic hyperplasia |
Type of Biomarker | Diagnostic |
Cohort | Training set: 25 patients with prostate cancer, 17 with Benign prostatic hyperplasia. Validation Set: 80 CaP, 44 BPH, and 54 healthy controls |
Senstivity | 90% |
Specificity | 62.96% |
AUC | 0.791 (95% CI: 0.709–0.872) |
Accuracy | NA |
Level Of Significance | Training: p= 0.0062 |
Method Used | Training Set: Microarrays, Validation set; qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on Independent Patient Cohort |
Technical Name | miR-940 |