| Biomarker ID | 848 |
| PMID | 22298030 |
| Year | 2012 |
| Biomarker | miR-622 |
| Biomarker Basis | Expression Based |
| Biomolecule | miRNA |
| Source | Plasma |
| Subjects | Humans |
| Regulation | Upregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:- DNA-binding transcription factor activity; positive regulation of gene expression; Pathways in cancer;regulation of cellular component organization; positive regulation of transcription, DNA-templated |
| Experiment | Prostate Cancer Vs Healthy Men |
| Type of Biomarker | Diagnostic |
| Cohort | Training set: 25 patients with prostate cancer, 17 with Benign prostatic hyperplasia. Validation Set: 80 CaP, 44 BPH, and 54 healthy controls |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | Testing: p<0.001 |
| Method Used | Training Set: Microarrays, Validation set; qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on Independent Patient Cohort |
| Technical Name | miR-622 |