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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID829
PMID22175903
Year2011
BiomarkerSecreted frizzled-related protein (SFRP)-2
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationDownregulated in Prostate cancer (PCa: 2.28 ± 0.33 Vs Controls: 1.11 ± 0.09)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-Wnt signaling pathway
ExperimentBenign Vs malignant prostate glands
Type of BiomarkerDiagnostic
Cohort216 patients with Prostate cancer and 37 controls (with Benign Prostatic Hyperplasia) were chosen for the study,
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.0001
Method UsedImmunohistochemistry
ClinicalNo
RemarksResults verified on rna (pcr) but not found significant
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameSFRP2