Biomarker ID | 816 |
PMID | 22117988 |
Year | 2011 |
Biomarker | ARHI |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Downregulated in aggressive Prostate Cancer (Aggressive:9.6 ± 1.2; Non Agressive: 8.3 ± 2.3 ) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Agressive Vs Non - Agressive Prostate Cancer |
Type of Biomarker | Prognostic |
Cohort | Tumour tissues from patients with non-aggressive (n = 18) or aggressive (n = 17) prostate cancer were taken for study. tumours of Gleason grade < 7 were designated as non-aggressive and those of Gleason grade ≥ 7 were designated as aggressive. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.001 |
Method Used | real-time reverse transcription–polymerase chain reaction (RT-PCR) |
Clinical | No |
Remarks | Expression of the housekeeping gene glyceraldehyde 3-phosphate dehydrogenase (GAPDH) was used as an internal control. ARHI mRNA levels relative to expression of the housekeeping gene: GAPDH) |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | ARHI |