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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID814
PMID22113713
Year2012
Biomarker(IL-7) Interleukin-7
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationAssociated with Prostate cancer specific Survival
Odds Ratio/Hazard Ratio/Relative RiskHR: 0.1 (95% CI: 0.02–0.86)
Effect on PathwaysPathways Include:-Cytokines and inflammatory response, Hematopoiesis regulation by cytokines, Interleukin-7 signaling pathway,Hematopoietic cell lineage,Signaling by interleukins
Experimentdisease specific survival Vs no survival
Type of BiomarkerPrognostic
Cohort44 patients with prostate cancer who ubderwent radical prosteactomy were chosen for the study.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.03
Method UsedqRT-PCR
ClinicalNo
RemarksMultivariate model considering Gleason Score, PSA, TGFb1 and IL-7. log-transformed expressions were used
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameIL7