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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID798
PMID22052531
Year2011
Biomarkerhsa-mir-375
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceSerum
SubjectsHumans
RegulationHigh expression associated with an increased risk of BCR
Odds Ratio/Hazard Ratio/Relative RiskHR: 4.23 (95% CI: 1.69-10.59)
Effect on PathwaysPathways Include(hsa-mir-375):-DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; nuclear chromatin; chromatin; nuclear chromosome
ExperimentBiochemical Recurrenece
Type of BiomarkerPrognostic
Cohort128 primary prostate cancers, 29 non-malignant tissues and 14 metastases were selected for the study. GEO accession number: GSE21036
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep = 0.002
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical Namehsa-mir-375