Biomarker ID | 798 |
PMID | 22052531 |
Year | 2011 |
Biomarker | hsa-mir-375 |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Serum |
Subjects | Humans |
Regulation | High expression associated with an increased risk of BCR |
Odds Ratio/Hazard Ratio/Relative Risk | HR: 4.23 (95% CI: 1.69-10.59) |
Effect on Pathways | Pathways Include(hsa-mir-375):-DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor activity; nuclear chromatin; chromatin; nuclear chromosome |
Experiment | Biochemical Recurrenece |
Type of Biomarker | Prognostic |
Cohort | 128 primary prostate cancers, 29 non-malignant tissues and 14 metastases were selected for the study. GEO accession number: GSE21036 |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p = 0.002 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | hsa-mir-375 |