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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID788
PMID22012634
Year2012
BiomarkerTTLL12+VAT1L+GGA1+RPIA+NHSL1+NOVA2+MAP2+PRPF38B+SRP14+ HSPH1+ZNF154+ADD1+RASSF7+RBM15+394 other genes
Biomarker BasisExpression Based
BiomoleculeProtein (Auto-antibodies)
SourceSerum
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
ExperimentProstate Cancer Vs Healthy Men
Type of BiomarkerDiagnostic
CohortFor Screening 20 patients and 20 controls were selected. For validation, 40 patients and 40 healthy controls and 40 benign disease patients were selected.
SenstivityNA
SpecificityNA
AUC0.69
AccuracyNA
Level Of Significancep<0.001
Method UsedMicroarray
ClinicalNo
RemarksResults are for 10 fold cross validation; Threshold for selecting protien: mean intensity plus 3 SD in the group of controls.
Clinical Trial NumberNA
Degree Of ValidityValidated on Independent Patient Dataset
Technical NameTTLL12, VAT1L, GGA1, RPIA, NHSL1, NOVA2, MAP2, PRPF38B, SRP14, HSPH1, ZNF154, ADD1, RASSF7, RBM15, 394