Biomarker ID | 788 |
PMID | 22012634 |
Year | 2012 |
Biomarker | TTLL12+VAT1L+GGA1+RPIA+NHSL1+NOVA2+MAP2+PRPF38B+SRP14+ HSPH1+ZNF154+ADD1+RASSF7+RBM15+394 other genes |
Biomarker Basis | Expression Based |
Biomolecule | Protein (Auto-antibodies) |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs Healthy Men |
Type of Biomarker | Diagnostic |
Cohort | For Screening 20 patients and 20 controls were selected. For validation, 40 patients and 40 healthy controls and 40 benign disease patients were selected. |
Senstivity | NA |
Specificity | NA |
AUC | 0.69 |
Accuracy | NA |
Level Of Significance | p<0.001 |
Method Used | Microarray |
Clinical | No |
Remarks | Results are for 10 fold cross validation; Threshold for selecting protien: mean intensity plus 3 SD in the group of controls. |
Clinical Trial Number | NA |
Degree Of Validity | Validated on Independent Patient Dataset |
Technical Name | TTLL12, VAT1L, GGA1, RPIA, NHSL1, NOVA2, MAP2, PRPF38B, SRP14, HSPH1, ZNF154, ADD1, RASSF7, RBM15, 394 |