| Biomarker ID | 787 |
| PMID | 22012634 |
| Year | 2012 |
| Biomarker | Auto-antibody profile (TTLL12+VAT1L+GGA1+RPIA+NHSL1+NOVA2+MAP2+PRPF38B+SRP14+ HSPH1+ZNF154+ADD1+RASSF7+RBM15+394 other genes) |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein (Auto-antibodies) |
| Source | Serum |
| Subjects | Humans |
| Regulation | Upregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | prostate cancer Vs benign disease |
| Type of Biomarker | Diagnostic |
| Cohort | For Screening 20 patients and 20 controls were selected. For validation, 40 patients and 40 healthy controls and 40 benign disease patients were selected. |
| Senstivity | NA |
| Specificity | NA |
| AUC | 0.71 |
| Accuracy | NA |
| Level Of Significance | p<0.001 |
| Method Used | Microarray |
| Clinical | No |
| Remarks | Results are for 10 fold cross validation; Threshold for selecting protien: mean intensity plus 3 SD in the group of controls. |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on Independent Patient Dataset |
| Technical Name | TTLL12 auto-antibody |