Biomarker ID | 753 |
PMID | 21917134 |
Year | 2011 |
Biomarker | NUF2 |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in Patients with Recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | HR = 2.28, (95% CI: 1.11-4.67) |
Effect on Pathways | Pathways Include:-M phase pathway,DNA replication,Cell cycle |
Experiment | PSA Reccurence Vs No Recurrence |
Type of Biomarker | Prognostic |
Cohort | Specimens from 72 clinically localized PCa cases with follow-up data (29 without recurrence and 43 with recurrence) and 17 clinically localized PCa without follow-up data were collected and frozen at the time of radical prostatectomy |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.0001 |
Method Used | real-time PCR |
Clinical | No |
Remarks | Univariate Analysis |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NUF2 |