Biomarker ID | 689 |
PMID | 21788966 |
Year | 2011 |
Biomarker | PCA3 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | Differentially Expressed |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include:- Primary bile acid biosynthesis, Bile acids and bile salt biosynthesis, Peroxisomal lipid metabolism, Bile acid and bile salt biosynthesis via 7-alpha-hydroxycholesterol, Bile acid and bile salt metabolism |
Experiment | Prostate Cancer Vs Non- Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | Total of 176 people were included in the study. A subset with PSA in range (3–15 ng/ml) were selcted out of which 62 had prostate Cancer and 24 did not have Prostate Cancer. |
Senstivity | NA |
Specificity | NA |
AUC | 0.569 (0.453–0.685) |
Accuracy | NA |
Level Of Significance | p=0.04 |
Method Used | qPCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | PCA3 |