| Biomarker ID | 689 |
| PMID | 21788966 |
| Year | 2011 |
| Biomarker | PCA3 |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Urine |
| Subjects | Humans |
| Regulation | Differentially Expressed |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include:- Primary bile acid biosynthesis, Bile acids and bile salt biosynthesis, Peroxisomal lipid metabolism, Bile acid and bile salt biosynthesis via 7-alpha-hydroxycholesterol, Bile acid and bile salt metabolism |
| Experiment | Prostate Cancer Vs Non- Prostate Cancer |
| Type of Biomarker | Diagnostic |
| Cohort | Total of 176 people were included in the study. A subset with PSA in range (3–15 ng/ml) were selcted out of which 62 had prostate Cancer and 24 did not have Prostate Cancer. |
| Senstivity | NA |
| Specificity | NA |
| AUC | 0.569 (0.453–0.685) |
| Accuracy | NA |
| Level Of Significance | p=0.04 |
| Method Used | qPCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | PCA3 |