Biomarker ID | 681 |
PMID | 21723797 |
Year | 2011 |
Biomarker | Lactate Dehydrogenase (LDH) |
Biomarker Basis | Expression Based |
Biomolecule | Metabolites |
Source | Plasma |
Subjects | Humans |
Regulation | Upregulated with increasing PSA |
Odds Ratio/Hazard Ratio/Relative Risk | OR>8.0 |
Effect on Pathways | Pathways Include:- Pyruvate metabolism and citric acid (TCA) cycle, Pyruvate metabolism, Myc active pathway, Glycolysis and gluconeogenesis, HIF-1 transcriptional activity in hypoxia |
Experiment | progression Vs No Progression |
Type of Biomarker | Prognostic |
Cohort | 21 patients with Prostate Cancer were chosen for this study |
Senstivity | 66.7% |
Specificity | 80% |
AUC | NA |
Accuracy | NA |
Level Of Significance | p= 0.014 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | LDHA |