| Biomarker ID | 681 |
| PMID | 21723797 |
| Year | 2011 |
| Biomarker | Lactate Dehydrogenase (LDH) |
| Biomarker Basis | Expression Based |
| Biomolecule | Metabolites |
| Source | Plasma |
| Subjects | Humans |
| Regulation | Upregulated with increasing PSA |
| Odds Ratio/Hazard Ratio/Relative Risk | OR>8.0 |
| Effect on Pathways | Pathways Include:- Pyruvate metabolism and citric acid (TCA) cycle, Pyruvate metabolism, Myc active pathway, Glycolysis and gluconeogenesis, HIF-1 transcriptional activity in hypoxia |
| Experiment | progression Vs No Progression |
| Type of Biomarker | Prognostic |
| Cohort | 21 patients with Prostate Cancer were chosen for this study |
| Senstivity | 66.7% |
| Specificity | 80% |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p= 0.014 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | LDHA |