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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID679
PMID21723797
Year2011
BiomarkermiR-141
Biomarker BasisExpression Based
BiomoleculemiRNA
SourcePlasma
SubjectsHumans
RegulationUpregulated with increasing PSA
Odds Ratio/Hazard Ratio/Relative RiskOR: 8.3
Effect on PathwaysPathways Include:- regulation of RNA metabolic process; Gene expression (Transcription); RNA Polymerase II Transcription; nuclear chromosome; DNA-binding transcription factor activity, RNA polymerase II-specific
Experimentprogression Vs No Progression
Type of BiomarkerPrognostic
Cohort21 patients with Prostate Cancer were chosen for this study
Senstivity78.9%
Specificity68.8%
AUCNA
AccuracyNA
Level Of Significancep<0.001
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NamemiR-141