Biomarker ID | 679 |
PMID | 21723797 |
Year | 2011 |
Biomarker | miR-141 |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Plasma |
Subjects | Humans |
Regulation | Upregulated with increasing PSA |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 8.3 |
Effect on Pathways | Pathways Include:- regulation of RNA metabolic process; Gene expression (Transcription); RNA Polymerase II Transcription; nuclear chromosome; DNA-binding transcription factor activity, RNA polymerase II-specific |
Experiment | progression Vs No Progression |
Type of Biomarker | Prognostic |
Cohort | 21 patients with Prostate Cancer were chosen for this study |
Senstivity | 78.9% |
Specificity | 68.8% |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.001 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | miR-141 |