| Biomarker ID | 673 |
| PMID | 21667031 |
| Year | 2011 |
| Biomarker | Androgen Receptor |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | RR: relative 2.05 (95% CI: 1.13-3.69) |
| Effect on Pathways | Pathways Include:- Prostate cancer,Androgen receptor signaling, proteolysis, and transcription regulation,SMAD2/3 nuclear pathway,Oocyte meiosis,SIDS susceptibility pathways |
| Experiment | Tumor Vs Normal Tissues |
| Type of Biomarker | Diagnostic |
| Cohort | 98 patients were taken for the study in which 31 had Adenocarcinoma, 18 had Prostatic intraepithelial neoplasia, 23 had peri Tumoral Tissue, and 24 had no malignancy. |
| Senstivity | 43% |
| Specificity | 90% |
| AUC | 0.5 (95% CI: 0.44-0.79) |
| Accuracy | NA |
| Level Of Significance | p=0.018 |
| Method Used | Real-time quantitative PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | AR |