Biomarker ID | 672 |
PMID | 21647377 |
Year | 2011 |
Biomarker | miR-145 |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Downregulated in Bone Metastatis |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include(miR-145):- positive regulation of transcription by RNA polymerase II; DNA-binding transcription activator activity, RNA polymerase II-specific; positive regulation of gene expression; Pancreatic adenocarcinoma pathway; positive regulation of cell population proliferation |
Experiment | Bone Metastatis Vs No Bone Metastasis |
Type of Biomarker | Prognostic |
Cohort | Samples of 16 primary PCa and 13 bone metastases were selected for analysis |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p=0.041 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | miR-145 |