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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID67
PMID15666362
Year2005
BiomarkerPhospholipase C
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsMice
RegulationUpregulated in PCa (1.95 fold)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- VEGF, hypoxia, and angiogenesis,Growth hormone receptor signaling ,Signaling by FGFR mutants, Netrin-1 signaling,Fc epsilon receptor I signaling in mast cells
ExperimentWild-type mouse dorsal prostate Vs Transgenic Adenocarcinoma Mouse Prostate (TRAMP) dorsal prostate
Type of BiomarkerDiagnostic
CohortProstate tissues from TRAMP F1 mice (TG) and wild-type mice (WT) were used in this study
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.05
Method Used2DIGE (2D-gel Electrophoresis)
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on human patient cohort
Technical NamePLCG1