Biomarker ID | 662 |
PMID | 21600800 |
Year | 2013 |
Biomarker | TMPRSS2:ERG+ PCA3 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | Differentially Expressed |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include(TMPRSS2):- Androgen receptor regulation of biosynthesis and transcription,Androgen receptor proteolysis and transcription regulation Pathways Include(ERG):-Genes targeted by miRNAs in adipocytes WP1992,VEGFA-VEGFR2 Signaling Pathway WP3888 |
Experiment | Prostate Cancer Vs No Prostate cancer |
Type of Biomarker | Diagnostic |
Cohort | 45 people were taken under consideration such that 15 had prostate cancer and 30 did not. |
Senstivity | NA |
Specificity | NA |
AUC | 0.82 |
Accuracy | NA |
Level Of Significance | NA |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | TMPRSS2, ERG, PCA3 |