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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID659
PMID21600800
Year2013
BiomarkerPSA
Biomarker BasisConcentration Based (ng/ml)
BiomoleculemRNA
SourceUrine
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskUnivariate: OR = 2.36; (95% CI: 0.54-12.54); p=0.011
Effect on PathwaysPathways Include :-ID regulation of gene expression,Prostate cancer, Androgen receptor proteolysis and transcription regulation, Androgen receptor signaling, proteolysis, and transcription regulation, Insulin-like growth factor (IGF) activity regulation by insulin-like growth factor binding proteins (IGFBPs)
ExperimentProstate Cancer Vs No Prostate cancer
Type of BiomarkerDiagnostic
Cohort45 people were taken under consideration such that 15 had prostate cancer and 30 did not.
Senstivity4000%
Specificity93%
AUC0.67 (95% CI: 0.53-0.81)
AccuracyNA
Level Of Significancep=0.019
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameKLK3