| Biomarker ID | 659 |
| PMID | 21600800 |
| Year | 2013 |
| Biomarker | PSA |
| Biomarker Basis | Concentration Based (ng/ml) |
| Biomolecule | mRNA |
| Source | Urine |
| Subjects | Humans |
| Regulation | Upregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | Univariate: OR = 2.36; (95% CI: 0.54-12.54); p=0.011 |
| Effect on Pathways | Pathways Include :-ID regulation of gene expression,Prostate cancer, Androgen receptor proteolysis and transcription regulation, Androgen receptor signaling, proteolysis, and transcription regulation, Insulin-like growth factor (IGF) activity regulation by insulin-like growth factor binding proteins (IGFBPs) |
| Experiment | Prostate Cancer Vs No Prostate cancer |
| Type of Biomarker | Diagnostic |
| Cohort | 45 people were taken under consideration such that 15 had prostate cancer and 30 did not. |
| Senstivity | 4000% |
| Specificity | 93% |
| AUC | 0.67 (95% CI: 0.53-0.81) |
| Accuracy | NA |
| Level Of Significance | p=0.019 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | KLK3 |