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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID65
PMID15666362
Year2005
BiomarkerProliferating cell nuclear antigen (PCNA)
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsMice
RegulationUpregulated in PCa (1.44 fold)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-Base excision repair, Global genomic nucleotide excision repair (,E2F-mediated regulation of DNA replicationGG-NER), DNA strand elongation,BARD1 signaling events
ExperimentWild-type mouse dorsal prostate Vs Transgenic Adenocarcinoma Mouse Prostate (TRAMP) dorsal prostate
Type of BiomarkerDiagnostic
CohortProstate tissues from TRAMP F1 mice (TG) and wild-type mice (WT) were used in this study
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.05
Method Used2DIGE (2D-gel Electrophoresis)
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on human patient cohort
Technical NamePCNA