Biomarker ID | 65 |
PMID | 15666362 |
Year | 2005 |
Biomarker | Proliferating cell nuclear antigen (PCNA) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Mice |
Regulation | Upregulated in PCa (1.44 fold) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-Base excision repair, Global genomic nucleotide excision repair (,E2F-mediated regulation of DNA replicationGG-NER), DNA strand elongation,BARD1 signaling events |
Experiment | Wild-type mouse dorsal prostate Vs Transgenic Adenocarcinoma Mouse Prostate (TRAMP) dorsal prostate |
Type of Biomarker | Diagnostic |
Cohort | Prostate tissues from TRAMP F1 mice (TG) and wild-type mice (WT) were used in this study |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | 2DIGE (2D-gel Electrophoresis) |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on human patient cohort |
Technical Name | PCNA |