| Biomarker ID | 649 |
| PMID | 21520154 |
| Year | 2011 |
| Biomarker | PSMA |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Urine |
| Subjects | Humans |
| Regulation | Downregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:-One-carbon metabolism,TNF-alpha effects on cytokine activity, cell motility, and apoptosis, T cell receptor regulation of apoptosis |
| Experiment | (Prostate Cancer Vs Benign) with PSA in range 4-10ng/ml |
| Type of Biomarker | Diagnostic |
| Cohort | Samples for Benign (n=54) and PCA (n=28) were taken into account for this study such that they had PSA in the range 4-10ng/ml. |
| Senstivity | 64% |
| Specificity | 70% |
| AUC | 0.74 |
| Accuracy | NA |
| Level Of Significance | p=0.003 |
| Method Used | qPCR |
| Clinical | No |
| Remarks | Briefly, 50% of the sample was used as a training set to compute a ROC curve. |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | FOLH1 |