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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID644
PMID21520154
Year2011
BiomarkerPSMA
Biomarker BasisExpression Based
BiomoleculemRNA
SourceUrine
SubjectsHumans
RegulationDownregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-One-carbon metabolism,TNF-alpha effects on cytokine activity, cell motility, and apoptosis, T cell receptor regulation of apoptosis
ExperimentProstate Cancer Vs Benign
Type of BiomarkerDiagnostic
CohortSamples for Benign (n=97) and PCA (n=57) were taken into account for this study.
Senstivity81%
Specificity41%
AUC0.62
AccuracyNA
Level Of Significancep=0.016
Method UsedqPCR
ClinicalNo
RemarksBriefly, 50% of the sample was used as a training set to compute a ROC curve.
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameFOLH1