Biomarker ID | 644 |
PMID | 21520154 |
Year | 2011 |
Biomarker | PSMA |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | Downregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-One-carbon metabolism,TNF-alpha effects on cytokine activity, cell motility, and apoptosis, T cell receptor regulation of apoptosis |
Experiment | Prostate Cancer Vs Benign |
Type of Biomarker | Diagnostic |
Cohort | Samples for Benign (n=97) and PCA (n=57) were taken into account for this study. |
Senstivity | 81% |
Specificity | 41% |
AUC | 0.62 |
Accuracy | NA |
Level Of Significance | p=0.016 |
Method Used | qPCR |
Clinical | No |
Remarks | Briefly, 50% of the sample was used as a training set to compute a ROC curve. |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | FOLH1 |