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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID643
PMID21519348
Year2011
BiomarkerKi-67/lum
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationUpregulated in Black men
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- RANKL regulation of apoptosis and immune response
ExperimentProstate Cancer in Black Men Vs Prostate Cancer in White Men
Type of BiomarkerPrognostic
Cohort131 patients having prostate cancer were taken for the study out of which 67 were black and 64 were white.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.022
Method UsedImmunofluorescence
ClinicalNo
RemarksMultivariate Analysis; lum = lumen area; Prostate cancer is more aggressive in Black men.
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameMKI67