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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID642
PMID21519348
Year2011
BiomarkerNorm AR (Androgen Receptor)
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationUpregulated in Black men
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- Prostate cancer,Androgen receptor signaling, proteolysis, and transcription regulation,SMAD2/3 nuclear pathway,Oocyte meiosis,SIDS susceptibility pathways
ExperimentProstate Cancer in Black Men Vs Prostate Cancer in White Men
Type of BiomarkerPrognostic
Cohort131 patients having prostate cancer were taken for the study out of which 67 were black and 64 were white.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of SignificanceUnivariate: p=0.006; Multivariate: p=0.001
Method UsedImmunofluorescence
ClinicalNo
RemarksUnivariate Analysis and Multivariate Analysis; Prostate cancer is more aggressive in Black men
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameAR