Biomarker ID | 642 |
PMID | 21519348 |
Year | 2011 |
Biomarker | Norm AR (Androgen Receptor) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in Black men |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:- Prostate cancer,Androgen receptor signaling, proteolysis, and transcription regulation,SMAD2/3 nuclear pathway,Oocyte meiosis,SIDS susceptibility pathways |
Experiment | Prostate Cancer in Black Men Vs Prostate Cancer in White Men |
Type of Biomarker | Prognostic |
Cohort | 131 patients having prostate cancer were taken for the study out of which 67 were black and 64 were white. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | Univariate: p=0.006; Multivariate: p=0.001 |
Method Used | Immunofluorescence |
Clinical | No |
Remarks | Univariate Analysis and Multivariate Analysis; Prostate cancer is more aggressive in Black men |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | AR |