Biomarker ID | 639 |
PMID | 21504578 |
Year | 2011 |
Biomarker | Desmin; Myosin regulatory light polypeptide 9; Serum deprivation-response protein 3; Sorbin and SH3 domain- containing protein 1; Tropomyosin alpha-1 chain; Protein kinase C delta-binding protein; Calponin-1; Vinculin; Prostatic acid phosphatase; Zyxin; Fibrinogen alpha chain; Histone H1.0; Talin-1; Protein disulfide-isomerase A3; |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Downregulated in PCA(Fold Change): |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs BPH with Local PIN |
Type of Biomarker | Diagnostic |
Cohort | Patients undergoing prostate Biopsies were divided into 3 groups, PCA (n=20), BPH (n=20) and PIN (n=10) |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | iTRAQ |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | DES, MYL9, CAVIN3, SORBS1, TPM1, PRKCD, CNN1, VCL, ACP3, ZYX, FGA, H1-0, TLN1, PDIA3 |