| Biomarker ID | 639 |
| PMID | 21504578 |
| Year | 2011 |
| Biomarker | Desmin; Myosin regulatory light polypeptide 9; Serum deprivation-response protein 3; Sorbin and SH3 domain- containing protein 1; Tropomyosin alpha-1 chain; Protein kinase C delta-binding protein; Calponin-1; Vinculin; Prostatic acid phosphatase; Zyxin; Fibrinogen alpha chain; Histone H1.0; Talin-1; Protein disulfide-isomerase A3; |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in PCA(Fold Change): |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Prostate Cancer Vs BPH with Local PIN |
| Type of Biomarker | Diagnostic |
| Cohort | Patients undergoing prostate Biopsies were divided into 3 groups, PCA (n=20), BPH (n=20) and PIN (n=10) |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | iTRAQ |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | DES, MYL9, CAVIN3, SORBS1, TPM1, PRKCD, CNN1, VCL, ACP3, ZYX, FGA, H1-0, TLN1, PDIA3 |