| Biomarker ID | 637 |
| PMID | 21504578 |
| Year | 2011 |
| Biomarker | Desmin; Serum deprivation-response protein 3; Sorbin and SH3 domain-containing protein 1; Vimentin; Calponin-1; Heat shock protein beta-1; Actin, gamma-enteric smooth muscle; Protein kinase C delta-binding protein; Collagen alpha-1(VI) chain Laminin subunit gamma-1; Sorbin and SH3 domain-containing protein 2; Tenascin; Zyxin; Talin-1; Collagen alpha-1(I) chain; Vinculin; Mimecan; Lipoma-preferred partner; Neuroblast differentiation-associated protein AHNAK; Decorin; Basement membrane-specific heparan sulfate proteoglycan core protein; Phosphatidylethanolamine-binding protein 1 |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated in PCA(Fold Change): |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Prostate Cancer Vs BPH |
| Type of Biomarker | Diagnostic |
| Cohort | Patients undergoing prostate Biopsies were divided into 3 groups, PCA (n=20), BPH (n=20) and PIN (n=10) |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | iTRAQ |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | DES, CAVIN2, SORBS1, VIM, CNN1, HSPB1, ACTB, ACTG2, PRKCD, LAMC1, SORBS2, TNC, ZYX, COL1A1, COL1A1, VCL, OGN, LPP, AHNAK, DCN, HSPG2, PEBP1 |