Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
Detailed Information | |
---|---|
Biomarker ID | 635 |
PMID | 21504557 |
Year | 2011 |
Biomarker | PSA |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include:-ID regulation of gene expression,Prostate cancer, Androgen receptor proteolysis and transcription regulation, Androgen receptor signaling, proteolysis, and transcription regulation, Insulin-like growth factor (IGF) activity regulation by insulin-like growth factor binding proteins (IGFBPs) |
Experiment | Prostate Cancer Vs BPH |
Type of Biomarker | Diagnostic |
Cohort | A total of 124 healthy donors along with 121 patients with BPH (or Prostatis) and 131 patients with prostate cancer were chosen for the study. |
Senstivity | 52% (68/131) |
Specificity | 79% (95/121) |
AUC | 0.66 |
Accuracy | 65% |
Level Of Significance | p<0.05 |
Method Used | SeroMAP-based assays and ELISA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | KLK3 |