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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID601
PMID21367627
Year2011
Biomarkervascular endothelial growth factor (VEGF)
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationUpregulated in Lymph Node Metastatis
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Inlude:- S1P/S1P3 pathway,VEGFR1 pathway,Heart development,Actions of nitric oxide in the heart,Fibroblast growth factor 1
ExperimentLymph Node Metastatis Posititve Lymph Node Metastatis Negative
Type of BiomarkerPrognostic
Cohort148 CaP patients who underwent radical prostatectomy for clinically localized disease and 10 samples of benign prostatic hyperplasia (BPH) were chosen for the study. Lymph Node Metastatis Posititve(n=10) and Lymph Node Metastatis Negative (n=138)
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.001
Method UsedImmunohistochemistry
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameVEGFA