| Biomarker ID | 57 |
| PMID | 15609297 |
| Year | 2005 |
| Biomarker | PSMA |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Upregulated (66 fold) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:-One-carbon metabolism,TNF-alpha effects on cytokine activity, cell motility, and apoptosis,T cell receptor regulation of apoptosis |
| Experiment | Prostate Cancer Vs benign prostatic hyperplasia |
| Type of Biomarker | Diagnostic |
| Cohort | 18 patients with prostate cancer and 35 patients with Benign Prostatic Hyperplasia (BPH) were tested against these 4 biomarkers to see how easily these 2 groups could be distinguished from one another |
| Senstivity | PCa Prediction: 47.6% |
| Specificity | BPH Prediction: 94.1% |
| AUC | NA |
| Accuracy | 76.5% |
| Level Of Significance | p=0.047 |
| Method Used | RT-PCR |
| Clinical | No |
| Remarks | The ratios of gene expression/10^5 copies of β2-microglobulin were calculated, in samples of PCa and BPH tissues |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | FOLH1 |