| Biomarker ID | 562 |
| PMID | 21060327 |
| Year | 2010 |
| Biomarker | ACADL; PHLDA2; GPD1; L; NTAN1; LOC389048; SFN; HSRG1; PAK1IP1; EBP; ANPEP; ANTXR2; COL4A6; LOC400880; RHOU; GREB1; FLJ30428; C3orf14; ZNF532; SCD; PTN; SC4MOL; MAF; NPAL3; CYP3A5; NOV; ALOX15B; LOC399959; VGL-3; INSIG1; Rcan3; Poteg; P704P; EFS; |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Downregulated (Fold Change): [ACADL (0.33 fold); PHLDA2 (0.33 fold); GPD1L (0.33 fold); NTAN1 (0.33 fold); LOC389048 (0.32 fold); SFN (0.32 fold); HSRG1 (0.32 fold); PAK1IP1 (0.32 fold); EBP (0.31 fold); ANPEP (0.31 fold); ANTXR2 (0.29 fold); COL4A6 (0.29 fold); LOC400880 (0.29 fold); RHOU (0.29 fold); GREB1 (0.28 fold); FLJ30428 (0.27 fold); C3orf14 (0.27 fold); ZNF532 (0.26 fold); SCD (0.25 fold); PTN (0.24 fold); SC4MOL (0.24 fold); MAF (0.22 fold); NPAL3 (0.22 fold); CYP3A5 (0.21 fold); NOV (0.20 fold); ALOX15B (0.17 fold); LOC399959 (0.17 fold); VGL-3 (0.16 fold); INSIG1 (0.16 fold); Rcan3 (0.15 fold); Poteg (0.14 fold); P704P (0.13 fold); EFS (0.13 fold)] |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include(EBM):- Steroid biosynthesis,Cholesterol biosynthesis,Lipid and lipoprotein metabolism,Metabolism Pathways Include(MAF):-GATA3-mediated activation of Th2 cytokine expression,Keap1-Nrf2 pathway,Regulation of NFAT transcription factors,AP-1 transcription factor network,C-Myb transcription factor network |
| Experiment | High BMI Tumor Vs High BMI Normal |
| Type of Biomarker | Diagnostic |
| Cohort | 6 patients with Normal BMI and 6 patients with High BMI were chosen for the study. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | ACADL, PHLDA2, GPD1, L, NTAN1, LOC389048, SFN, HSRG1, PAK1IP1, EBP, ANPEP, ANTXR2, COL4A6, LOC400880, RHOU, GREB1, FLJ30428, C3orf14, ZNF532, SCD, PTN, SC4MOL, MAF, NPAL3, CYP3A5, NOV, ALOX15B, LOC399959, VGL-3, INSIG1, Rcan3, POTEG, P704P, EFS |