Biomarker ID | 559 |
PMID | 20977276 |
Year | 2011 |
Biomarker | HSP60 |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:-Myc active pathway,Mitochondrial pathway of apoptosis: caspases,Endogenous Toll-like receptor signaling, Mitochondrial protein import, Protein metabolism |
Experiment | Gleason 6 Vs Benign Prostate |
Type of Biomarker | Diagnostic |
Cohort | 46 patients were chosen for the study such that 23 had a gleason score of 6 and 23 had a score of 8 or higher. |
Senstivity | NA |
Specificity | NA |
AUC | 0.89 |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | HSPD1 |