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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID559
PMID20977276
Year2011
BiomarkerHSP60
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-Myc active pathway,Mitochondrial pathway of apoptosis: caspases,Endogenous Toll-like receptor signaling, Mitochondrial protein import, Protein metabolism
ExperimentGleason 6 Vs Benign Prostate
Type of BiomarkerDiagnostic
Cohort46 patients were chosen for the study such that 23 had a gleason score of 6 and 23 had a score of 8 or higher.
SenstivityNA
SpecificityNA
AUC0.89
AccuracyNA
Level Of Significancep<0.05
Method UsedImmunohistochemistry
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameHSPD1