Biomarker ID | 543 |
PMID | 20957673 |
Year | 2011 |
Biomarker | PCA3 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | Differentially Expressed |
Odds Ratio/Hazard Ratio/Relative Risk | Univariate: OR: 1.123 (95% CI: 1.054 – 1.198); Multivariate: OR: 1.082 (95% CI: 1.012 – 1.156) |
Effect on Pathways | NA |
Experiment | Cancer Vs No Malignancy (PSA Range: 4-10) |
Type of Biomarker | Diagnostic |
Cohort | 86 untreated patients with CaP and 45 patients with no evidence of malignancy |
Senstivity | NA |
Specificity | NA |
AUC | 0.733 (95% CI: 0.635-0.831) |
Accuracy | NA |
Level Of Significance | Univariate: p=0; Multivariate: p=0.02 |
Method Used | Quantitative PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | PCA3 |