| Biomarker ID | 537 |
| PMID | 20632874 |
| Year | 2010 |
| Biomarker | AR: (Short CAG) |
| Biomarker Basis | Mutation Based |
| Biomolecule | Mutation |
| Source | Blood |
| Subjects | Humans |
| Regulation | Increased RIsk of GS (4+3) with Short CAG Repeats |
| Odds Ratio/Hazard Ratio/Relative Risk | OR: 8.8 (95% CI:1.06–73.05) |
| Effect on Pathways | Pathways Include:- Prostate cancer,Androgen receptor signaling, proteolysis, and transcription regulation,SMAD2/3 nuclear pathway,Oocyte meiosis,SIDS susceptibility pathways |
| Experiment | Gleason Score 7 (4+3) Vs Gleason Score 7 (3+4) |
| Type of Biomarker | Prognostic |
| Cohort | 170 patients who underwent radical prosteactomy were taken for this study along with 170 controls. 82 had Gleason Score >=7 and 88 have gleason Score <7. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p = 0.045 |
| Method Used | PCR-RFLP (restriction fragment length polymorphism) |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | AR |