CTYPE html> ProCanBio | Biomarker Card

Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID534
PMID20632874
Year2010
BiomarkerAR: (Short CAG)
Biomarker BasisMutation Based
BiomoleculeMutation
SourceBlood
SubjectsHumans
RegulationIncreased Risk with shorter CAG Repeats
Odds Ratio/Hazard Ratio/Relative RiskOR: 1.89 (95% CI: 1.21–2.96)
Effect on PathwaysPathways Include:- Prostate cancer,Androgen receptor signaling, proteolysis, and transcription regulation,SMAD2/3 nuclear pathway,Oocyte meiosis,SIDS susceptibility pathways
ExperimentCancer Vs Controls
Type of BiomarkerDiagnostic
Cohort160 patients who underwent radical prosteactomy were taken for this study along with 160 controls.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep = 0.007
Method UsedPCR-RFLP (restriction fragment length polymorphism)
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameAR