Biomarker ID | 528 |
PMID | 20473869 |
Year | 2010 |
Biomarker | miRNA-141 |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:- regulation of RNA metabolic process; Gene expression (Transcription); RNA Polymerase II Transcription; nuclear chromosome; DNA-binding transcription factor activity, RNA polymerase II-specific |
Experiment | Gleason Score >8 Vs Gleason Score 7 |
Type of Biomarker | Prognostic |
Cohort | Second validation study took serum samples of 71 patients. Gleason Score >=8(n = 29), Gleason Score 7(n = 42) |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.01 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on Independent Patient Dataset |
Technical Name | miRNA-141 |