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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID528
PMID20473869
Year2010
BiomarkermiRNA-141
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceSerum
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- regulation of RNA metabolic process; Gene expression (Transcription); RNA Polymerase II Transcription; nuclear chromosome; DNA-binding transcription factor activity, RNA polymerase II-specific
ExperimentGleason Score >8 Vs Gleason Score 7
Type of BiomarkerPrognostic
CohortSecond validation study took serum samples of 71 patients. Gleason Score >=8(n = 29), Gleason Score 7(n = 42)
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.01
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on Independent Patient Dataset
Technical NamemiRNA-141