| Biomarker ID | 520 |
| PMID | 20392989 |
| Year | 2010 |
| Biomarker | CB:SA ratio: (cathepsin B/stefin A) |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Upregulated in Cancer: (BPH Geometric Mean : 1.448 Vs Cancer Geometric Mean : 2.990) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include (CTSB):- Toll-like receptor endosomal trafficking and processing, Antigen processing and presentation, Mitochondrial pathway of apoptosis: BH3-only Bcl-2 family, MHC class II antigen presentation, Lysosome |
| Experiment | benign prostatic hyperplasia Vs Prostate Cancer |
| Type of Biomarker | Diagnostic |
| Cohort | Prostate needle biopsy specimens and matched RPs from 47 patients with cancer were evaluated. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.0001 |
| Method Used | Immunohistochemistry |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | CTSB, CSTA |