| Biomarker ID | 514 |
| PMID | 20087897 |
| Year | 2010 |
| Biomarker | Enhancer of Zeste 2 (EZH2) |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Cell Lines |
| Subjects | Humans |
| Regulation | Overexpression leads to aggressive behaviour in Cell Lines |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways Include:- Cell differentiation pathway,MicroRNAs in muscle cell differentiation, PRC2 complex long-term gene silencing through modification of histone tails,Interleukin-2 signaling pathway |
| Experiment | Overexpression Vs No Overexpression in Cell Lines |
| Type of Biomarker | Prognostic |
| Cohort | 5 cell lines were used BPH1, CWR22Rv1, PC3, DU145, and LNCaP for the experiment. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | NA |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | EZH2 |