CTYPE html> ProCanBio | Biomarker Card

Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID51
PMID15609297
Year2005
BiomarkerPSMA+Hepsin+DD3
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:-Proteins Involved in Prostate Cancer
ExperimentProstate Cancer Vs benign prostatic hyperplasia
Type of BiomarkerDiagnostic
Cohort18 patients with prostate cancer and 32 patients woth Benign Prostatic Hyperplasia (BPH) were tested against these 4 biomarkers to see how easily these 2 groups could be distinguished from one another
SenstivityBPH Prediction: 100%
SpecificityPCa Prediction: 100%
AUCNA
Accuracy10000%
Level Of SignificanceNA
Method UsedRT-PCR
ClinicalNo
RemarksThe ratios of gene expression/10^5 copies of β2-microglobulin were calculated, in samples of PCa and BPH tissues
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NamePSMA, HPN, PCA3