Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 487 |
| PMID | 20672322 |
| Year | 2010 |
| Biomarker | PCA3 (Prostate Cancer Gene 3) |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Urine |
| Subjects | Humans |
| Regulation | Upregulated |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Benign Vs Prostate Cancer |
| Type of Biomarker | Diagnostic |
| Cohort | The study population consisted of 215 men, 73(34%) were positive for PCa and 142 (66%) were negative (benign controls without cancer |
| Senstivity | 0.69 [0.56-0.79] |
| Specificity | 0.59 [0.50-0.67] |
| AUC | 0.66 [0.58-0.73] |
| Accuracy | NA |
| Level Of Significance | p<0.001 |
| Method Used | qPCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | PCA3 |