Biomarker ID | 486 |
PMID | 20672322 |
Year | 2010 |
Biomarker | PSGR (Prostate-Specific G-protein Coupled Receptor) |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | Upregulated |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:- Olfactory transduction,Signaling by GPCR |
Experiment | Benign Vs Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | The study population consisted of 215 men, 73(34%) were positive for PCa and 142 (66%) were negative (benign controls without cancer |
Senstivity | 0.59 [0.47-0.70] |
Specificity | 0.73 [0.65 - 0.80] |
AUC | 0.68 [0.61-0.76] |
Accuracy | NA |
Level Of Significance | p=0.008 |
Method Used | qPCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | OR51E2 |