| Biomarker ID | 482 |
| PMID | 20632177 |
| Year | 2010 |
| Biomarker | PSA |
| Biomarker Basis | Concentration Based (ng/ml) |
| Biomolecule | Protein |
| Source | Serum |
| Subjects | Humans |
| Regulation | Upregulated in PCa |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include:-ID regulation of gene expression,Prostate cancer,Androgen receptor proteolysis and transcription regulation,Androgen receptor signaling, proteolysis, and transcription regulation,Insulin-like growth factor (IGF) activity regulation by insulin-like growth factor binding proteins (IGFBPs) |
| Experiment | Prostate Cancer Vs No Tumor |
| Type of Biomarker | Diagnostic |
| Cohort | 113 men were chosen for the study out of which 79 had no tumor and 34 had Prostate Cancer. |
| Senstivity | 97.1% [95% (CI) = 82.9–99.8] |
| Specificity | 17.7% [95% CI: 10.4–28.3]. |
| AUC | 0.476 ± 0.1 |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | NA |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | KLK3 |