Biomarker ID | 482 |
PMID | 20632177 |
Year | 2010 |
Biomarker | PSA |
Biomarker Basis | Concentration Based (ng/ml) |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include:-ID regulation of gene expression,Prostate cancer,Androgen receptor proteolysis and transcription regulation,Androgen receptor signaling, proteolysis, and transcription regulation,Insulin-like growth factor (IGF) activity regulation by insulin-like growth factor binding proteins (IGFBPs) |
Experiment | Prostate Cancer Vs No Tumor |
Type of Biomarker | Diagnostic |
Cohort | 113 men were chosen for the study out of which 79 had no tumor and 34 had Prostate Cancer. |
Senstivity | 97.1% [95% (CI) = 82.9–99.8] |
Specificity | 17.7% [95% CI: 10.4–28.3]. |
AUC | 0.476 ± 0.1 |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | NA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | KLK3 |